Internal beam radiation therapy is a type of treatment for cancer in which radioactive materials are inserted or implanted at the cancer site inside the body.
Internal beam radiation therapy works by damaging the DNA within the cancer cells such that they are unable to divide and grow any further. DNA is a type of genetic code that controls the way the cells of the body behave.
Types:
Purpose:
Depending on the type of procedure being performed, internal radiation therapy may be used to treat the following types of cancers:
Radioactive liquid treatment: The following different types of radioactive liquids may be used to treat different types of cancers like:
Iodine-131: Thyroid cancer and benign (non-cancerous) thyroid disorders
Phosphorus or P-32: Certain blood disorders
Radium-223: Secondary bone cancer (cancer that has spread to the bones)
Strontium-89: Secondary bone cancers
Brachytherapy: It is used to treat the following types of cancers:
Breast cancer
Brain cancer
Bile duct cancer
Endometrial cancer
Eye cancer
Esophageal cancer
Soft tissue cancers
Lung cancer
Cervical cancer
Head and neck cancers
Prostate cancer
Pancreatic cancer
Skin cancer
Rectal cancer
Vaginal cancer
The following diagnostic tests could be performed before an internal beam radiation therapy procedure:
Depending on the type of procedure being performed, internal beam radiation therapy can be done in the following ways:
1. Radioactive liquid treatment:
The patient may be given radioactive liquid treatment in the form of a capsule, drink, or injection.
The different types of radioactive liquids used may include iodine-131, radium-223, phosphorus-32, or strontium-89.
The radioactive portion of the liquid is known as an isotope. It could be attached to another substance, which is designed in a manner to take the isotope into the tumor.
The radioactive liquid will travel through the body, but it mainly collects in the areas where the cancer is located, causing minimal damage to the surrounding healthy cells of the body.
2. Brachytherapy:
Most brachytherapy implants are placed in the body using a catheter (a small, stretchy tube). Sometimes, brachytherapy implants may be placed in the body through a larger device, called an applicator. The catheter or applicator is placed into the body before starting the treatment.
Once the catheter or applicator is in its place, the radiation source is later placed inside it. The radiation source must be kept in its place for a few minutes for several days, or for the remaining life of the patient depending on the type of radiation source used, location of cancer, type of cancer present, the condition of the patient, and other forms of cancer treatments that the patient has undergone.
The different techniques used for brachytherapy are:
Interstitial brachytherapy: This technique involves the placement of the radiation source within the tumor, like within the prostate or breast.
Intracavitary brachytherapy: This technique involves the placement of the radiation source within a body cavity or a cavity created by surgery, like a vagina or windpipe.
Episcleral brachytherapy: This technique involves the attachment of the radiation source to the eye and is used to treat melanoma of the eye.
Internal beam radiation therapy may have the following side effects:
Fatigue
Hair loss
Urinary incontinence (involuntary urine leakage)
Difficulty in urinating
Cough
Erectile dysfunction
Bowel incontinence (involuntary stool passage)
Dyspnea (shortness of breath)
Constipation
Diarrhea
Mouth ulcers
Headaches
Nausea
Vomiting
The radiation source in the body may give off radiation for some time after internal beam radiation therapy. You will therefore need to take certain safety measures after internal radiation therapy like:
Stay in the private hospital room and protect other people from radiation coming from your body.
Hospital visits by visitors are to be avoided completed or done only at a safe distance after wearing protective gear.
Avoid any contact with young children or pregnant women.
The catheter is removed after treatment completion using LDR or HDR implants.
The doctor prescribes pain-relieving medications before catheter or applicator removal.
It is normal to have tenderness in the catheter or applicator placement area for a few months.
After the removal of the catheter or applicator there is no radiation left in your body and it is safe for you to be around other people.
After the removal of the catheter, you may need to limit your daily activities for one or two weeks.
Follow-up visits and scans are advised by the doctor to check how successful was the treatment.
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